Epidemiological studies forming the framework for recommending use of the a1c to diagnose diabetes have all been in adult populations. whether the cut point would be the same to diagnose children or adolescents with type 2 diabetes is an area of uncertainty (3,10). a1c inaccurately reflects glycemia with certain anemias and hemoglobinopathies.. Fructosamine is clearly superior in patients with abnormal hemoglobins because of the interference of abnormal hemoglobins in the anion-exchange chromatography methods for hb a1c. published reference interval for apparently healthy subjects between age 20 and 60 is 205−285 μmol/l and in a poorly-controlled diabetic population is 228−563.
Fructosamine is clearly superior in patients with abnormal hemoglobins because of the interference of abnormal hemoglobins in the anion-exchange chromatography methods for hb a1c. published reference interval for apparently healthy subjects between age 20 and 60 is 205−285 μmol/l and in a poorly-controlled diabetic population is 228−563. Biochemistry.pdf – free ebook download as pdf file (.pdf), text file (.txt) or read book online for free..
The average bg to a1c conversion equation is not perfect most (if not all) average bg to a1c conversion tables and calculators use the below equation to estimate a1c: average bg (mg/dl) = 28.7 x a1c (%) – 46.7 this equation is based on data from a 2008 study of over 500 subjects (268 t1ds, 159 t2ds, and 80 non-diabetics) at 10 international. Biochemistry.pdf – free ebook download as pdf file (.pdf), text file (.txt) or read book online for free..
In australia, both methods are reported concurrently. a conversion equation is as follows: ngsp (%) = 0.0915 × ifcc (mmol/mol) fructosamine is an alternative marker of glucose levels, radin ms. pitfalls in hemoglobin a1c measurement: when results may be misleading. j gen intern med 2014;29(2):388–94. doi: 10.1007/s11606-013-2595-x..
